4.56. In the assessment of safety in the operational stage, similar approaches are applied to those applied for predisposal management of radioactive waste as described in Ref. [27]. Also relevant for the operation of disposal facilities are Safety Requirements and Safety Guides for the operation of nuclear power plants, such as Refs [28, 29]. In addition, other issues, such as mining safety, may need to be considered in the assessment of safety in the operational stage of a disposal facility (e.g. in the case of deep geological disposal). Applicable requirements for non-radiological aspects (e.g. those for occupational health and safety) should be applied in an integrated manner with those for radiological aspects; how this is achieved will depend on the type of facility, the legal and regulatory framework, and the stage of facility development.