4.52. Elements of good scientific practice include, among other things, making observations, developing and testing hypotheses, assessing reproducibility and peer review. The application of good scientific principles in the development of a safety case can be illustrated by considering, for example, work aimed at developing an understanding of groundwater flow at a particular site. Such work might involve taking surface and borehole measurements, putting forward hypotheses on influences on groundwater flow, testing these hypotheses with models using the data collected, using more than one approach or team in the modelling work to examine alternative conceptual models and their reproducibility, and subjecting the work to independent peer review (see paras 4.92?4.94).